A priceless 12th-century illustrated manuscript containing what has been described as Europe's first travel guide has been stolen from the cathedral at Santiago de Compostela in northern Spain.

The Codex Calixtinus, which was kept in a safe at the cathedral's archives, is thought to have been stolen by professional thieves on Sunday afternoon. Archivists did not notice its disappearance, however, until Tuesday, when the cathedral's dean was told it was missing.

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